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Updated: Jul 28, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Visible light-mediated three-component functionalization of olefins with sulfoxyimidoylsulfonium salt for the
Wei Xie1, Liang Zhao1, Xinmei Fu1
1State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, Liaoning, P.R. China. ymli@dlut.edu.cn.
Abstract:
A new strategy involving three-component functionalization of olefins with sulfoxyimidoylsulfonium salt and a nucleophilic reagent for the synthesis of β-amino alcohols and β-amino ethers by photoredox catalysis was developed. The sulfoxyimidoylsulfonium salt is important and serves as the N-centred radical precursor. β-Amino alcohols and β-amino ethers bearing various functional groups are synthesized in good yields under mild conditions. Furthermore, the advantages of this strategy are greater safety, no additives, and easy to obtain raw materials.
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