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Published on: September 8, 2023
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Evaluation of missing data imputation methods for human osteometric measurements
1USF Genomics & College of Public Health, University of South Florida, Tampa, Florida, USA.
American Journal of Biological Anthropology
|June 1, 2023
Summary
This study evaluated statistical methods for imputing missing skeletal data in bioarcheology and forensics. Multiple imputation techniques, like Bayesian linear regression and Expectation-Maximization (EM) with Bootstrapping, proved more accurate and robust than single imputation methods.
Area of Science:
- Bioarcheology
- Forensic Anthropology
- Quantitative Biology
Background:
- Bioarcheological and forensic analyses often involve incomplete skeletal specimens.
- Many multivariate statistical methods require complete data, necessitating missing data imputation.
Purpose of the Study:
- To evaluate the performance of popular statistical methods for imputing missing metric measurements in skeletal data.
- To identify accurate, robust, and efficient imputation techniques for bioarcheological and forensic applications.
Main Methods:
- Utilized William W. Howells' Craniometric Data Set and the Goldman Osteometric Data Set.
- Compared performance of single imputation methods (e.g., Bayesian Principal Component Analysis - BPCA) against multiple imputation methods.
- Evaluated methods including Bayesian linear regression (norm2), Expectation-Maximization (EM) with Bootstrapping (Amelia), and Predictive Mean Matching (PMM) (mice).
Main Results:
- Multiple imputation methods significantly outperformed single imputation methods.
- Bayesian linear regression (norm2), EM with Bootstrapping (Amelia), and PMM (mice) demonstrated strong performance in accuracy, robustness, and speed.
- Bayesian Principal Component Analysis (BPCA) was identified as a less effective single imputation method.
Conclusions:
- Multiple imputation techniques are recommended for handling missing data in skeletal analyses.
- A practical procedure for selecting appropriate imputation methods based on study findings is proposed.
- The study provides guidance for biological anthropologists working with incomplete skeletal data.

