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Evaluation of missing data imputation methods for human osteometric measurements.

Jinyong Pang1, Xiaoming Liu1

  • 1USF Genomics & College of Public Health, University of South Florida, Tampa, Florida, USA.

American Journal of Biological Anthropology
|June 1, 2023
PubMed
Summary

This study evaluated statistical methods for imputing missing skeletal data in bioarcheology and forensics. Multiple imputation techniques, like Bayesian linear regression and Expectation-Maximization (EM) with Bootstrapping, proved more accurate and robust than single imputation methods.

Keywords:
craniometricsimputationmissing dataosteometrics

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Area of Science:

  • Bioarcheology
  • Forensic Anthropology
  • Quantitative Biology

Background:

  • Bioarcheological and forensic analyses often involve incomplete skeletal specimens.
  • Many multivariate statistical methods require complete data, necessitating missing data imputation.

Purpose of the Study:

  • To evaluate the performance of popular statistical methods for imputing missing metric measurements in skeletal data.
  • To identify accurate, robust, and efficient imputation techniques for bioarcheological and forensic applications.

Main Methods:

  • Utilized William W. Howells' Craniometric Data Set and the Goldman Osteometric Data Set.
  • Compared performance of single imputation methods (e.g., Bayesian Principal Component Analysis - BPCA) against multiple imputation methods.
  • Evaluated methods including Bayesian linear regression (norm2), Expectation-Maximization (EM) with Bootstrapping (Amelia), and Predictive Mean Matching (PMM) (mice).

Main Results:

  • Multiple imputation methods significantly outperformed single imputation methods.
  • Bayesian linear regression (norm2), EM with Bootstrapping (Amelia), and PMM (mice) demonstrated strong performance in accuracy, robustness, and speed.
  • Bayesian Principal Component Analysis (BPCA) was identified as a less effective single imputation method.

Conclusions:

  • Multiple imputation techniques are recommended for handling missing data in skeletal analyses.
  • A practical procedure for selecting appropriate imputation methods based on study findings is proposed.
  • The study provides guidance for biological anthropologists working with incomplete skeletal data.