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Gestational age and socio-demographic factors associated with school performance at the age of 12 years, a
Renée J Burger1,2, Tessa J Roseboom1,2, Wessel Ganzevoort1,2
1Department of Obstetrics and Gynaecology, Amsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Insights
Higher gestational age is linked to better school performance up to 40 weeks. Children born preterm, especially those from disadvantaged backgrounds, face increased risks for lower academic achievement.
Area of Science:
- Pediatrics
- Developmental Psychology
- Public Health
Background:
- Gestational age positively correlates with cognitive development.
- Socio-demographic factors significantly influence school performance.
- Prematurity may pose increased risks for children with low socioeconomic status (SES).
Purpose of the Study:
- To investigate the association between gestational age, socio-demographic characteristics, and school performance at age 12.
- To explore potential interactions between gestational age and socio-demographic factors on school outcomes.
Main Methods:
- Population-based cohort study of 860,332 liveborn singletons in the Netherlands (1999-2006).
- Analysis of school performance data from 2011 to 2019.
- Regression analyses to assess associations and interactions.
Main Results:
- School performance increased with gestational age up to 40 weeks.
- Preterm birth (25 weeks) was associated with significantly lower school performance z-scores and secondary school level compared to 40 weeks.
- Low maternal education, low maternal age, non-European origin, later birth order, and low SES were associated with lower school performance.
- Evidence of interaction: preterm children from disadvantaged backgrounds (low education, low/high maternal age, low SES, later birth order) were at higher risk.
Conclusions:
- Higher gestational age is associated with better school performance across the entire gestational age spectrum.
- Children in socially or economically disadvantaged situations may be more vulnerable to the adverse effects of preterm birth.
- Maternal education, maternal age, ethnicity, birth order, and SES are crucial factors influencing school performance.
Background:
Gestational age is positively associated with cognitive development, but socio-demographic factors also influence school performance. Previous studies suggested possible interaction, putting children with low socio-economic status (SES) at increased risk of the negative effects of prematurity.
Objectives:
To investigate the association between gestational age in weeks, socio-demographic characteristics, and school performance at the age of 12 years among children in regular primary education.
Methods:
Population-based cohort study among liveborn singletons (N = 860,332) born in the Netherlands in 1999-2006 at 25-42 weeks' gestation, with school performance from 2011 to 2019. Regression analyses were conducted investigating the association of gestational age and sociodemographic factors with school performance and possible interaction.
Results:
School performance increased with gestational age up to 40 weeks. This pattern was evident across socio-demographic strata. Children born at 25 weeks had -0.57 SD (95% confidence interval -0.79, -0.35) lower school performance z-scores and lower secondary school level compared to 40 weeks. Low maternal education, low maternal age, and non-European origin were strongly associated with lower school performance. Being born third or later and low socioeconomic status (SES) were also associated with lower school performance, but differences were smaller than among other factors. When born preterm, children from mothers with low education level, low or high age, low SES or children born third or later were at higher risk for lower school performance compared to children of mothers with intermediate education level, aged 25-29 years, with intermediate SES or first borns (evidence of interaction).
Conclusions:
Higher gestational age is associated with better school performance at the age of 12 years along the entire spectrum of gestational age, beyond the cut-off of preterm birth and across socio-demographic differences. Children in socially or economically disadvantaged situations might be more vulnerable to the negative impact of preterm birth. Other important factors in school performance are maternal education, maternal age, ethnicity, birth order and SES. Results should be interpreted with caution due to differential loss to follow-up.
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