Related Experiment Video
Updated: Jul 28, 2025

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
TS-1 Synthesis via Subcrystal Aggregation: Construction of Highly Active Hydrogen-Bonded Titanium Species for Alkene
Di Pan1, Lingtao Kong1, Hongbin Zhang2
1Department of Chemistry, Laboratory of Advanced Materials, Collaborative Innovation Center of Chemistry for Energy Materials and Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, China.
Abstract:
The construction and determination of highly active Ti sites comprise one of the most significant challenges in the rational design and synthesis of Ti-containing porous catalysts. The pathway to efficiently build highly catalytically active titanium species remains to be proposed in spite of deliberate post treatments or ambiguous batch composition adjustments. In this study, we developed a bottom-up strategy to construct a TS-1 catalyst with highly active hydrogen-bonded Ti species via subcrystal aggregation crystallization. The microstructure of the hydrogen-bonded Ti species was verified by vacuum FT-IR and 1H MAS SSNMR spectroscopies. Noteworthy features of the hydrogen-bonded Ti species were also revealed, including a pentahedral coordination state and Brønsted acidity, as identified by the UV-Raman, XPS, XAFS, and FT-IR spectra of adsorbed pyridine. Significantly, the hydrogen-bonded Ti species exhibits extraordinary activity in allyl chloride epoxidation (nearly 70% higher than that of traditional Ti species). This study provides a new approach to building highly active Ti sites, which may provide new insights into the design and synthesis of high-performance titanosilicate catalysts.
More Related Videos
Related Concept Videos
Sharpless Epoxidation
Radical Substitution: Hydrogenolysis of Alkyl Halides with Tributyltin Hydride
The bonds formed in this reaction are stronger than the bonds broken, making it energetically favorable. The reaction follows a radical chain mechanism similar to radical halogenation...
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Alkenes via Reductive Coupling of Aldehydes or Ketones: McMurry Reaction
Preparation of Epoxides
Epoxides result from alkene oxidation, which can be achieved by a) air, b) peroxy acids, c) hypochlorous acids, and d) halohydrin cyclization.
Epoxidation with Peroxy Acids
Epoxidation of alkenes via oxidation with peroxy acids involves the conversion of a carbon–carbon double bond to an epoxide using the oxidizing agent meta-chloroperoxybenzoic acid, commonly known as MCPBA. Since the O–O bond of peroxy acids is very weak, the addition of electrophilic oxygen of...
Oxidation of Alkenes: Anti Dihydroxylation with Peroxy Acids

