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Asthma innovations from the first International Collaborative Asthma Network forum
Benjamin Gaston1, Donna D Gardner2, Kenzie Mahan1
1Indiana University, Indianapolis, IN, USA.
ERJ Open Research
|June 1, 2023
Summary
The International Collaborative Asthma Network (ICAN) fosters global research into non-T2 inflammation asthma mechanisms. This network aims to drive innovation and collaboration for new asthma treatments beyond current therapies.
Area of Science:
- * Pulmonology and immunology research focusing on severe asthma.
- * Investigating novel therapeutic targets and disease mechanisms.
- * Cross-disciplinary approaches to understanding complex respiratory diseases.
Background:
- * Uncontrolled asthma affects many patients despite existing treatments.
- * Current therapies predominantly target type 2 (T2) inflammation.
- * Significant need exists for research into non-T2 asthma mechanisms.
Purpose of the Study:
- * Establish the International Collaborative Asthma Network (ICAN) for global asthma research.
- * Facilitate sharing of innovative research on asthma disease mechanisms.
- * Promote development of new technologies, therapies, and pilot studies.
Main Methods:
- * Solicited abstracts from early-stage investigators focusing on non-T2 asthma.
- * Selected innovative research beyond T2 inflammation for presentation.
- * Organized breakout sessions on innovation, collaboration, and research translation.
Main Results:
- * Abstracts covered omics, lung-brain axis, sex differences, pediatric asthma, and new therapeutics.
- * Research groups seek collaboration for large-scale studies.
- * Emphasis on translating in vitro findings into clinical treatments.
Conclusions:
- * ICAN unites interdisciplinary early-stage investigators in asthma research.
- * The network fosters discussion on innovation, collaboration, and translation.
- * ICAN provides a model for future global collaborative asthma research.
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