A Rare Case of Leuconostoc pseudomesenteroides Bacteremia and Refractory Septic Shock

Mike Ghobrial1, Mohamed Ibrahim2, Spencer G Streit1

  • 1Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Cureus
|June 1, 2023
PubMed

Insights

Leuconostoc pseudomesenteroides, a rare cause of bacteremia, is often misidentified and resistant to antibiotics. This case highlights the importance of considering this pathogen in drug-resistant infections, even when rare.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Bacteriology

Background:

  • Leuconostoc species are uncommon causes of bloodstream infections (bacteremia).
  • These bacteria are frequently misidentified as Streptococcus species.
  • Inherent antimicrobial resistance in Leuconostoc often leads to delayed or incorrect treatment.

Observation:

  • A 29-year-old male presented with out-of-hospital cardiac arrest.
  • Initial resuscitation was successful, but the patient's condition deteriorated.
  • A rare bloodstream infection with Leuconostoc pseudomesenteroides was diagnosed.

Findings:

  • The patient's infection was caused by Leuconostoc pseudomesenteroides.
  • This pathogen is intrinsically resistant to many commonly used antibiotics.
  • Misidentification and drug resistance contributed to poor patient outcomes.

Implications:

  • Clinicians should consider Leuconostoc species in cases of severe, drug-resistant bacteremia.
  • Accurate identification of Leuconostoc is crucial for appropriate antimicrobial therapy.
  • Increased awareness may improve outcomes for patients with these rare infections.

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