Related Experiment Video
Updated: Jul 28, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Lung Function Tests in Infants and Children
Kana Ram Jat1, Sheetal Agarwal2,3
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India. drkanaram@gmail.com.
Insights
Lung function tests offer objective insights into pediatric lung health, aiding diagnosis and monitoring from infancy through adolescence. Proper interpretation of spirometry, forced oscillation technique (FOT), and other pulmonary function tests (PFTs) is crucial for effective treatment.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
Background:
- Lung function testing is vital for diagnosing and monitoring pediatric lung diseases.
- Technological advancements enable objective assessment of lung health across all age groups, from neonates to adults.
Purpose of the Study:
- To review current lung function tests applicable to infants and children.
- To highlight the diagnostic and monitoring capabilities of various pulmonary function tests (PFTs).
Main Methods:
- Narrative review of available literature on pediatric lung function testing.
- Discussion of spirometry, peak expiratory flow rate (PEFR), forced oscillation technique (FOT)/impulse oscillometry (IOS), infant PFT equipment, diffusion capacity for carbon monoxide (DLCO), and lung volume assessment techniques.
Main Results:
- Spirometry and PEFR are standard for children over six, diagnosing obstructive and restrictive diseases.
- FOT/IOS are feasible in preschool children, primarily for asthma assessment.
- Infant PFT equipment, DLCO, and lung volume techniques (body plethysmography, multiple washout) offer further diagnostic capabilities.
Conclusions:
- Lung function tests are essential for pediatric respiratory care, requiring expertise for accurate performance and interpretation.
- Correct interpretation and clinical correlation of PFT results are paramount for optimal patient outcomes.
Abstract:
Lung function testing is an essential modality of investigation in children as it provides objective evidence of lung disease/health. With advances in technology, various tests are available that can aid in the diagnosis of lung disease, assess the progression and response to therapy and document the lung development and evolving lung diseases in infants. This narrative review discusses lung function tests in infants and children. Currently, lung function tests can be performed in every age group, from neonates to the elderly. Spirometry and peak expiratory flow rate (PEFR) are the most employed tests in children more than six years of age. Spirometry helps diagnose and monitoring of both obstructive and restrictive diseases. There is a need for expertise to perform and interpret spirometry correctly. The forced oscillation technique (FOT) or impulse oscillometry (IOS) is done with tidal volume breathing and is feasible even in preschool children. Their utility is mainly restricted to asthma in children at present. Lung function tests can be performed in neonates, infants and children using infant pulmonary function test (PFT) equipment, although their availability is limited. Diffusion capacity for carbon monoxide (DLCO) is a valuable tool in restrictive lung diseases. Lung volumes can be assessed by body plethysmography and multiple washout technique. The latter can also assess lung clearance index. It is essential to perform and interpret the lung function test results correctly and correlate them with the clinical condition for optimum treatment and outcome.
Related Concept Videos
Pulmonary Function Tests
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Respiratory Volumes
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Lung Capacity
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration...
Pulmonary Cycle: Exhalation
Respiratory Capacities
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...

