Related Experiment Video
Updated: Jul 28, 2025

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
A randomized controlled trial of an information intervention to bolster COVID-19 vaccination intention among people
Catherine Chen1, Zhihan Cui2, Yixi Chen3
1Department of Communication, Stanford University.
Objective:
Previous literature has indicated a strong negative correlation between the moral foundation of purity/sanctity and vaccination rates. The current research investigated how purity concerns impact COVID-19 vaccination hesitancy and tested an information intervention to bolster vaccination intention among people with purity concerns.
Method:
Study 1 surveyed 566 Republicans and Republican-leaning Independents in the United States. Study 2 was a between-subject-designed survey experiment that investigated the impact of three statements on the COVID-19 vaccination attitudes and intentions of 637 Republicans and Republican-leaning Independents. Statement 1 argued that vaccines are not impure from a scientific perspective; Statement 2 made the same argument with quotes from the Bible; and Statement 3 was a control statement.
Results:
Study 1 established a significant correlation between the existence of vaccination history and purity as a moral foundation. Study 2 found that among those with no COVID-19 vaccination history, statements arguing that vaccines are not impure from either a scientific perspective or a religious perspective improved attitudes toward vaccination and intention to get vaccinated.
Conclusion:
Purity concerns can be leveraged as a way to bolster vaccination rates, especially among conservatives. However, the impurity perception only mediated the causal relationship between the treatment and the attitude toward vaccines (but not the actual intention), suggesting that changes in the actual vaccination behavior are subject to factors other than purity concerns. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
More Related Videos
06:05The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
Published on: February 19, 2021
07:40Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
Published on: May 31, 2021
Related Concept Videos
Vaccinations
Blinding
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...