PhenoBR: a model to phenotype body condition dynamics in meat sheep

In situations of negative energy balance (NEB) due to feed scarcity or high physiological demands, body energy reserves (BRs), mainly stored in adipose tissues, become the main sources of energy for ruminants. The capacity to mobilise and restore such BRs in response to different challenges is of major concern in the current context of breeding for resilience. Body condition score (BCS) is a common, practical indicator of BR variations throughout successive productive cycles, and quantitative tools for characterising such dynamics at the individual level are still lacking. The main objective of this work was to characterise body condition dynamics in terms of BR mobilisation and accretion capacities of meat sheep during their productive lifespan through a modelling approach, using BCS measurements. The animal model used in this work was the reproductive meat ewe (n = 1 478) reared in extensive rangeland. Regular measurements of BCS for each productive cycle were used as the indicator of BR variations. A hybrid mathematical model and a web interface, called PhenoBR, were developed to characterise ewes' BCS variations through four synthetic and biologically meaningful parameters for each productive cycle i: BR accretion rate (k_bⁱ), BR mobilisation rate (k_pⁱ), plus the time of onset and the duration of the BR mobilisation, t_bⁱ and ΔTⁱ, respectively. The model PhenoBR converged for all the ewes included in the analysis. Estimation of the parameters indicated the inter-individual variability for BR accretion and mobilisation rates, and the length of the mobilisation period. The present study is a proof of concept that the combination of data-driven and concept-driven models is required for the estimation of biologically meaningful parameters that describe body reserve dynamics through consecutive productive cycles. Individual characterisation of animals by these parameters makes it possible to rank them for their efficiency in the use of body reserves when facing NEB challenges. Such parameters could contribute to better management and decision-making by farmers and advisors, e.g. by adapting feeding systems to the individual characteristics of BR dynamics, or by geneticists as criteria to develop future animal breeding programmes including BR dynamics for more robust and resilient animals.