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The Use of Stereotactic Radiosurgery to Treat Functional Disorders: A Topic Discussion
Grace Simmons1, Matthew Gallitto1, Albert Lee1
1Department of Radiation Oncology, Columbia University Irving Medical Center, New York, New York.
Practical Radiation Oncology
|June 1, 2023
Summary
Stereotactic radiosurgery (SRS) effectively treats malignant brain tumors and offers therapeutic potential for non-malignant functional disorders like epilepsy and pain. This review consolidates current applications and guides clinical practice.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Neurology
Background:
- Stereotactic radiosurgery (SRS) is established for malignant brain tumors.
- Its application for benign functional disorders is less explored.
- Limited prospective data exists for these indications.
Purpose of the Study:
- To consolidate the application of SRS for functional disorders.
- To serve as a reference for clinicians considering SRS for benign conditions.
- To discuss SRS for epilepsy, tremor, trigeminal neuralgia, OCD, and pain.
Main Methods:
- Literature review and discussion of existing data.
- Consolidated analysis of SRS application in functional disorders.
- Synthesis of current clinical practice guidelines.
Main Results:
- SRS demonstrates potential in treating various functional disorders.
- Evidence supports SRS for epilepsy, tremor, trigeminal neuralgia, OCD, and pain.
- Further prospective studies are needed to guide optimal treatment.
Conclusions:
- SRS is a viable treatment option for select functional neurological disorders.
- This review provides a reference for SRS application in benign conditions.
- Future research should focus on prospective trials for evidence-based guidelines.
