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Updated: Jul 28, 2025
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Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care
Published on: September 22, 2023
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Is it enough to observe less than 2 cm sized gastric SET?
In Kyung Yoo1, Young Kwan Cho2, Seong Whan Kim2
1Division of Gastroenterology, Department of Internal Medicine, Cha Bundang Medical Center, Cha University College of Medicine, Seongnam-si, South Korea.
Surgical Endoscopy
|June 1, 2023
Summary
Endoscopic resection is effective for small gastric subepithelial tumors (SETs) under 2 cm. This study found a notable percentage of GISTs among these small SETs, highlighting their potential for malignant transformation.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Endoscopic Therapeutics
Background:
- Increased detection of gastric subepithelial tumors (SETs) due to enhanced screening endoscopy.
- Current guidelines recommend surveillance for SETs < 2 cm.
- Advancements in therapeutic endoscopy enable resection of small SETs.
Purpose of the Study:
- To analyze histopathological features of small gastric SETs.
- To evaluate the effectiveness of endoscopic resection for small gastric SETs.
- To assess the risk of malignancy in small gastric SETs.
Main Methods:
- Retrospective analysis of 74 patients undergoing endoscopic resection of gastric SETs (≤ 2 cm).
- Evaluation of histopathology and en bloc resection outcomes.
- Analysis of procedure time and patient outcomes.
Main Results:
- Mean SET size was 11.69 mm; mean procedure time was 81.26 min.
- Histopathological diagnoses included leiomyomas (28), GISTs (26), ectopic pancreas (14), lipomas (4), and neuroendocrine tumors (2).
- Two GIST cases showed high-risk histology; all resections were successful and uneventful.
Conclusions:
- Endoscopic resection is a viable option for small gastric SETs (< 2 cm).
- Small gastric SETs include a significant proportion of GISTs, which have malignant potential.
- Early detection and resection of small SETs are crucial for managing potential GISTs.
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