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Hannah Trøstrup1, Anand Loya2, Niels Obel3

  • 1Afdeling for Plastikkirurgi og Brandsårsbehandling, Københavns Universitetshospital - Rigshospitalet.

Ugeskrift for Laeger
|June 2, 2023
PubMed
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This case report details a rare instance of cutaneous malakoplakia, an inflammatory condition, in a kidney transplant recipient. It highlights the importance of recognizing this unusual presentation in immunocompromised patients.

Area of Science:

  • Immunology
  • Dermatology
  • Pathology

Background:

  • Malakoplakia is a chronic inflammatory condition typically affecting internal organs, often linked to E. coli infections in immunocompromised individuals.
  • It arises from impaired macrophage function, leading to granulomatous inflammation.

Observation:

  • A rare case of cutaneous malakoplakia occurred in the left axilla of a 48-year-old male kidney transplant recipient.
  • The patient presented with a one-year history post-transplant.

Findings:

  • Cutaneous malakoplakia presents with diverse clinical features, including nodules, plaques, and moist wounds.
  • The condition is associated with Eschericia coli infection and macrophage dysfunction.

Implications:

Related Experiment Videos

  • This case underscores the variability of malakoplakia presentation, extending to cutaneous manifestations.
  • Early diagnosis and long-term antibiotic therapy are crucial for managing this rare inflammatory condition in transplant patients.