Ketogenic diet in cancer management

Area of Science:

• Oncology
• Nutrition Science
• Metabolic Research

Background:

• The ketogenic diet (KD) is characterized by high fat, moderate protein, and very-low carbohydrate intake.
• Emerging evidence suggests KD possesses anticancer properties and can enhance conventional cancer therapies.
• KD's mechanism involves selectively targeting cancer cell metabolism while sparing normal cells.

Approach:

• This review synthesizes information on various KD types.
• It details the anticancer mechanisms of KD.
• It examines KD's application in preclinical and clinical cancer studies.

Key Points:

• Multiple experimental and clinical studies support KD as an adjuvant cancer therapy.
• KD interventions are being explored for various cancer types.
• The diet's metabolic effects offer a novel approach to cancer treatment.

Conclusions:

• The reviewed studies provide a strong foundation for further research into KD as an adjunct cancer treatment.
• KD represents a potential complementary strategy to conventional oncology interventions.
• Further investigation is warranted to optimize KD protocols for cancer patients.