Related Experiment Video

Updated: Jul 28, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
04:24

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

11.6K

A prospective, randomized, controlled, multicentre trial for secondary prevention in patients with chronic coronary

Philip Düsing1, Irina Eckardt1, Stephan H Schirmer2

  • 1Department of Medicine II, Heart Center, University Hospital Bonn, Venusberg Campus 1, 53127 Bonn, Germany.

European Heart Journal. Digital Health
|June 2, 2023
PubMed

Insights

The CHANGE study evaluates a smartphone app for improving secondary prevention adherence and quality of life in chronic coronary syndrome (CCS) patients. This digital tool aims to optimize care for individuals with this leading cause of global mortality.

Area of Science:

  • Cardiology
  • Digital Health
  • Preventive Medicine

Background:

  • Coronary artery disease (CAD), now termed chronic coronary syndrome (CCS), is a major global cause of mortality.
  • Despite advances, CCS patients face high morbidity and mortality rates.
  • Optimal secondary prevention is crucial, involving risk factor modification and lifestyle changes.

Purpose of the Study:

  • To investigate the efficacy of a smartphone application in enhancing secondary prevention adherence among CCS patients.
  • To assess the impact of a digital health intervention on the quality of life (QoL) for individuals with CCS.
  • To provide evidence for optimizing secondary prevention strategies in CCS management.

Main Methods:

  • Prospective, randomized, controlled trial with 210 CCS patients across nine German centers.
  • 1:1 allocation to either standard-of-care or standard-of-care plus the VantisTherapy* smartphone app.
  • Outcomes measured at 0, 12, and 24 weeks, focusing on adherence to secondary prevention guidelines and QoL.

Main Results:

  • The study is ongoing, with recruitment initiated in July 2022.
  • Primary outcomes focus on adherence and QoL, with data collected over 24 weeks.
  • The trial is registered under DRKS00028081.

Conclusions:

  • The CHANGE study will determine if a smartphone-guided app improves adherence and QoL in CCS patients compared to standard care.
  • This research explores the potential of digital tools in managing chronic conditions like CCS.
  • Findings may inform future digital health strategies for cardiovascular disease prevention.
Abstract

Keywords:
Chronic coronary syndromeDigital healthSecondary prevention

More Related Videos

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders05:58

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

Published on: February 3, 2021

3.6K
A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.3K

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
12
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
15
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
25
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
12