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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Articles linked to this work by shared authors, journal, and citation graph.

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Third Generation Genome Sequencing of the Endobacterium Corynebacterium kroppenstedtii subsp. demodicis Reveals Details of Its Microbe-Host-Interaction With the Most Complex Human Commensal, Demodex folliculorum.

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Related Experiment Video

Updated: Jul 28, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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[Current dermatology guidelines in Germany-selected recommendations from 2021 and 2022].

A Pennitz1, E Breitbart2, B M Clanner-Engelshofen3

  • 1Division of Evidence-Based Medicine (dEBM), Klinik für Dermatologie, Venerologie und Allergologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. antonia.pennitz@charite.de.

Dermatologie (Heidelberg, Germany)
|June 2, 2023
PubMed
Summary

German dermatological guidelines were updated in 2021-2022 on various conditions including psoriasis and rosacea. These guidelines provide decision-making support for appropriate clinical care in dermatology.

Keywords:
DermatologyDiagnosisDiseaseSkinTherapy

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Area of Science:

  • Dermatology
  • Evidence-Based Medicine

Context:

  • Dermatological guidelines are crucial decision-making aids for clinical care.
  • In Germany, guidelines are developed by the German Dermatological Society (DDG) and the Professional Association of German Dermatologists (BVDD).
  • European and international guidelines are published by organizations like EuroGuiDerm and the European Dermatology Forum (EDF).

Purpose:

  • To summarize key recommendations and innovations from recently revised and developed German dermatological guidelines.
  • To highlight updates in clinical care for specific dermatological conditions.

Summary:

  • In 2021 and 2022, German guidelines were revised or developed for conditions including anticoagulation management, chronic pruritus, contact dermatitis, laser therapy, psoriasis vulgaris, rosacea, extracorporeal photopheresis, onychomycosis, mucous membrane pemphigoid, and skin cancer prevention.
  • The summary focuses on the most important recommendations and innovations within these updated guidelines.

Impact:

  • Facilitates appropriate clinical care by providing up-to-date, evidence-based recommendations for dermatologists.
  • Ensures consistent and high-quality management of various skin conditions across Germany.
  • Contributes to the advancement of dermatological practice through the integration of new findings and therapeutic approaches.