Related Experiment Video

Updated: Jul 28, 2025

Probiotic Studies in Neonatal Mice Using Gavage
10:36

Probiotic Studies in Neonatal Mice Using Gavage

Published on: January 27, 2019

19.6K

Upper gastrointestinal series in healthy neonates with bilious vomiting-is it still obvious? A retrospective

Audelia Eshel Fuhrer1, Reut Doyev2, Tal Koppelmann1

  • 1Department of Pediatric Surgery, Dana-Dwek Children's hospital, Tel Aviv Sourasky medical center, Tel Aviv, Israel.

Acta Paediatrica (Oslo, Norway : 1992)
|June 2, 2023
PubMed

Insights

Upper gastrointestinal contrast series (UGI) remain crucial for diagnosing malrotation and midgut volvulus (MGV) in neonates with bilious vomiting (BV). Clinical signs like abnormal X-rays and distention increase suspicion but do not replace UGI.

Area of Science:

  • Pediatric Surgery
  • Diagnostic Imaging
  • Neonatal Care

Background:

  • Bilious vomiting (BV) in neonates often necessitates ruling out malrotation and midgut volvulus (MGV).
  • Demand for upper gastrointestinal contrast series (UGI) has risen due to increased awareness of MGV.

Purpose of the Study:

  • To evaluate the predictive value of clinical parameters in managing neonates with BV.
  • To reassess the role of UGI in diagnosing malrotation and MGV in neonates presenting with BV.

Main Methods:

  • Retrospective cohort study.
  • Inclusion of medical, imaging, and surgical data from 157 term neonates who underwent UGI for BV.

Main Results:

  • Eight neonates (5.1%) were diagnosed with malrotation, five with MGV, including two requiring intestinal resection for necrosis.
  • Abnormal plain radiographs combined with abdominal distention increased malrotation odds by 10 times (p=0.017).
  • Abnormal radiographs, distention, and tenderness raised MGV odds by 25 times (p=0.002).

Conclusions:

  • UGI remains the primary diagnostic tool for neonatal malrotation and MGV.
  • Clinical findings and plain radiographs are supportive but insufficient to replace UGI studies.
Abstract

Keywords:
bilious vomitingfluoroscopyintestinal malrotationmidgut volvulusupper GI contrast series

More Related Videos

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates06:10

Extrahepatic Bile Duct and Gall Bladder Dissection in Nine-Day-Old Mouse Neonates

Published on: August 23, 2022

2.0K
Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture05:33

Author Spotlight: Alleviating Nausea and Vomiting in Pregnancy with Safe and Effective Auricular Acupuncture

Published on: August 4, 2023

1.4K

Related Concept Videos

Upper GI Series: Barium Swallow01:24

Upper GI Series: Barium Swallow

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...
557
Lower GI Series: Barium Enema01:23

Lower GI Series: Barium Enema

A Barium Enema, or a lower GI series, is a specialized radiographic examination designed to visualize the lower gastrointestinal tract, specifically the colon and rectum. This procedure is instrumental in diagnosing various conditions such as colorectal cancer, polyps, diverticulosis, and inflammatory bowel disease.
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
346
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
115
Pathophysiology of Vomiting01:22

Pathophysiology of Vomiting

Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
680
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
231
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
236