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Nonsterile Basics of Compounding: Compounding with Humectants
1International Journal of Pharmaceutical Compounding. lallen@ijpc.com.
International Journal of Pharmaceutical Compounding
|June 2, 2023
Summary
Humectants are widely used in pharmaceuticals, foods, and cosmetics. Selecting the right humectant for pharmaceutical formulations requires careful consideration of dosage form, ingredients, and stability.
Area of Science:
- Pharmaceutical Sciences
- Cosmetic Science
- Food Science
Background:
- Humectants are essential excipients with broad applications in pharmaceuticals, food, and cosmetics.
- Their selection is critical for formulation success, influencing product performance and stability.
- Understanding humectant properties is key for effective pharmaceutical development.
Purpose of the Study:
- To provide an overview of commonly used humectants.
- To detail humectants specifically utilized in pharmaceutical formulations.
- To discuss the physicochemical characteristics influencing humectant selection in pharmaceuticals.
Main Methods:
- Literature review of common humectants across industries.
- Compilation of typical humectants in pharmaceutical applications.
- Analysis of physicochemical properties relevant to pharmaceutical use.
Main Results:
- Identified common humectants in pharmaceuticals, foods, and cosmetics.
- Presented a detailed list of pharmaceutical humectants.
- Included physicochemical characteristics for pharmaceutical humectants.
Conclusions:
- Humectant selection in pharmaceuticals is multifactorial, involving dosage form, ingredients, and stability.
- Physicochemical properties are crucial for optimizing humectant performance in drug products.
- This review aids formulators in choosing appropriate humectants for pharmaceutical applications.
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