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Updated: Jul 28, 2025

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Published on: February 23, 2024

Potential applications of Fe

B N Swathi¹, B R Radha Krushna¹, M V Manjula²

¹Prof. C.N.R. Rao Centre for Advanced Materials, Tumkur University, Tumkur 572 103, India.

Biomaterials Advances

|June 2, 2023

Summary

This summary is machine-generated.

This study synthesized Fe3+-activated Sr9Al6O18 nanophosphors (SAO:Fe NPs) for enhanced latent fingerprint detection. These SAO:Fe NPs also demonstrate significant antioxidant and anti-thrombotic properties, suggesting dual applications in forensics and medicine.

Keywords:

Combustion method Latent fingerprints detection Nanophosphors Thrombosis

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Published on: February 27, 2021

Area of Science:

Materials Science
Forensic Science
Biomedical Science

Background:

Latent fingerprint (LFP) detection is crucial in forensics.
Novel nanomaterials are needed to improve LFP visualization sensitivity and specificity.
SAO:Fe NPs exhibit promising fluorescence properties.

Purpose of the Study:

To synthesize Fe3+-activated Sr9Al6O18 nanophosphors (SAO:Fe NPs).
To evaluate SAO:Fe NPs for latent fingerprint detection.
To investigate the biomedical potential of SAO:Fe NPs in combating oxidative stress and thrombosis.

Main Methods:

Solution combustion synthesis for SAO:Fe NPs.
In-situ powder dusting and UV (254 nm) excitation for LFP visualization.
Deep convolutional neural networks (YOLOv8x) for fingerprint feature analysis.
DPPH scavenging assay and RBC oxidative stress models for antioxidant activity.
ADP-induced platelet aggregation assay for anti-thrombotic potential.

Main Results:

SAO:Fe NPs exhibit bright pale green fluorescence with high contrast and sensitivity for LFPs.
Effective visualization of LFPs on diverse surfaces with no background interference.
SAO:Fe NPs demonstrated significant antioxidant capacity and normalized oxidative stress markers.
SAO:Fe NPs successfully inhibited platelet aggregation.

Conclusions:

SAO:Fe NPs are effective for sensitive and specific latent fingerprint detection.
SAO:Fe NPs possess significant antioxidant and anti-thrombotic activities.
These nanophosphors show potential for dual applications in forensic science and advanced cardiology.