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Related Experiment Video

Updated: Jul 28, 2025

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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Commonly prescribed medications associated with alopecia.

Jessica Mounessa1, Joseph V Caravaglio2, Renee Domozych2

  • 1Stony Brook University School of Medicine, Stony Brook, New York; Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Journal of the American Academy of Dermatology
|June 2, 2023
PubMed
Summary

This study identified 13 commonly prescribed medications linked to hair loss in high-quality research. Further investigation is needed to understand the mechanisms of drug-induced alopecia for better patient management.

Keywords:
adverse eventsalopeciaanagen effluviumchemotherapy-induceddrug-inducedhair dystrophyhair lossmedication-inducedtelogen effluvium

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Area of Science:

  • Pharmacology
  • Dermatology
  • Evidence-Based Medicine

Background:

  • Medication-associated alopecia presents diagnostic and therapeutic challenges for patients and physicians.
  • Existing research on drug-induced hair loss lacks comprehensive analysis of study strength and magnitude.

Purpose of the Study:

  • To identify commonly prescribed medications with robust evidence linking them to alopecia.
  • To assess the strength of evidence for drug-associated hair loss.

Main Methods:

  • Compiled lists of top-selling and most-searched medications.
  • Conducted systematic literature searches in PubMed, Embase, and Web of Science for drug names and alopecia/hair loss.
  • Two independent reviewers evaluated study type, evidence level, and case numbers.

Main Results:

  • Investigated 192 unique drugs, with 110 showing positive search results for alopecia association.
  • Identified 13 medications with strong evidence linking them to hair loss, including adalimumab, infliximab, and docetaxel.

Conclusions:

  • High-quality evidence linking specific medications to alopecia remains limited.
  • Further research into the mechanisms of drug-induced hair loss is crucial for effective management strategies.