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A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
Published on: March 9, 2015
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Commonly prescribed medications associated with alopecia
Jessica Mounessa1, Joseph V Caravaglio2, Renee Domozych2
1Stony Brook University School of Medicine, Stony Brook, New York; Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Journal of the American Academy of Dermatology
|June 2, 2023
Summary
This study identified 13 commonly prescribed medications linked to hair loss in high-quality research. Further investigation is needed to understand the mechanisms of drug-induced alopecia for better patient management.
Area of Science:
- Pharmacology
- Dermatology
- Evidence-Based Medicine
Background:
- Medication-associated alopecia presents diagnostic and therapeutic challenges for patients and physicians.
- Existing research on drug-induced hair loss lacks comprehensive analysis of study strength and magnitude.
Purpose of the Study:
- To identify commonly prescribed medications with robust evidence linking them to alopecia.
- To assess the strength of evidence for drug-associated hair loss.
Main Methods:
- Compiled lists of top-selling and most-searched medications.
- Conducted systematic literature searches in PubMed, Embase, and Web of Science for drug names and alopecia/hair loss.
- Two independent reviewers evaluated study type, evidence level, and case numbers.
Main Results:
- Investigated 192 unique drugs, with 110 showing positive search results for alopecia association.
- Identified 13 medications with strong evidence linking them to hair loss, including adalimumab, infliximab, and docetaxel.
Conclusions:
- High-quality evidence linking specific medications to alopecia remains limited.
- Further research into the mechanisms of drug-induced hair loss is crucial for effective management strategies.
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