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Updated: Jul 28, 2025

A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Mandibular reconstruction after excision of recurrent odontogenic keratocyst using a novel mandibular distraction
Haiyun Lin1,2,3, Xiaoxia Zhong4, Nuo Zhou1,2,3
1Department of Oral and Maxillofacial Surgery, College & Hospital of Stomatology, Guangxi Medical University, Nanning, 530021, People's Republic of China.
Background:
Odontogenic keratocyst is one of the most common benign odontogenic neoplasms with a high recurrence rate. Its resection has the potential to lead to mandibular segmental defects. In this case report, we describe a patient with odontogenic keratocyst who underwent radical resection using a novel distraction osteogenesis (DO) method to reconstruct mandibular segmental defect.
Case Presentation:
This case report describes a 19-year-old woman with odontogenic keratocyst of the mandible that recurred after multiple curettages and eventually necessitated radical resection. Mandibular segmental defect after radical resection was reconstructed using a novel DO method that involved directly contacting the segment ends of the defect without the transport disk. However, the distractor broke during the retention period, and a molding titanium plate was used for fixation. This novel distraction method achieved mandibular reconstruction and restored mandibular function and contour.

