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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
38
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

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AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
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Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

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Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

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Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
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Cardiovascular issues in rheumatic diseases.

Olena Zimba1,2,3, Armen Yuri Gasparyan4

  • 1Department of Clinical Rheumatology and Immunology, University Hospital in Krakow, Macieja Jakubowskiego 2, 30-688, Krakow, Poland. zimbaolena@gmail.com.

Clinical Rheumatology
|June 3, 2023
PubMed
Summary
This summary is machine-generated.

Cardiovascular disease is a significant concern in rheumatic diseases. Systemic inflammation intensity strongly predicts vascular events, necessitating improved monitoring and prevention strategies for patients and specialists.

Keywords:
AutoimmunityCardiovascular preventionHeartInflammationPrediction toolsRheumatic diseaseVessels

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Area of Science:

  • Rheumatology
  • Cardiology
  • Immunology

Background:

  • Cardiovascular disease (CVD) is a leading cause of death in rheumatic diseases like rheumatoid arthritis and systemic lupus erythematosus.
  • While inflammation is a known factor, accurate cardiovascular risk estimation in rheumatic diseases remains challenging, complicated by atherogenesis in conditions like fibromyalgia and osteoarthritis.
  • Systemic inflammation intensity is linked to vascular events in inflammatory rheumatic diseases, highlighting the need for better risk assessment tools.

Purpose of the Study:

  • To highlight the prevalence and significance of cardiovascular affections in rheumatic diseases.
  • To address the critical issue of cardiovascular risk estimation in the context of rheumatic diseases.
  • To advocate for enhanced cardiovascular monitoring and prevention strategies.

Main Methods:

  • Review of existing literature on cardiovascular disease in rheumatic diseases.
  • Analysis of cohort studies associating systemic inflammation with vascular events.
  • Discussion of advanced visualization techniques for cardiovascular monitoring.
  • Emphasis on patient and specialist education for risk factor management.

Main Results:

  • Cardiovascular issues are common across all age groups in rheumatic diseases.
  • Systemic inflammation intensity is a powerful predictor of vascular events in these patients.
  • Current tools for predicting vascular events in inflammatory rheumatic diseases are not widely validated or reliable.

Conclusions:

  • Tight control of systemic inflammation and modifiable cardiovascular risk factors is crucial for reducing vascular event risk.
  • Improving knowledge and skills in cardiovascular monitoring and prevention for patients and specialists is essential.
  • Empowering patients and primary care providers with knowledge is a promising strategy to mitigate cardiovascular risks in rheumatic diseases.