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Tick Microbiome Characterization by Next-Generation 16S rRNA Amplicon Sequencing
Published on: August 25, 2018
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The chigger microbiome: big questions in a tiny world.
Kittipong Chaisiri1, Piyada Linsuwanon2, Benjamin L Makepeace3
1Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Ratchathewi, Bangkok 10400, Thailand.
Trends in Parasitology
|June 3, 2023
Summary
Chiggers (trombiculid mite larvae) carry diverse bacteria and viruses, not just those causing scrub typhus. Evidence suggests chiggers may transmit these pathogens vertically to offspring.
Area of Science:
- Microbiology
- Vector-borne diseases
- Arthropod-borne pathogens
Background:
- Chiggers (trombiculid mite larvae) are recognized vectors of Orientia spp., the causative agents of scrub typhus.
- Recent findings indicate chiggers harbor a broader range of pathogens, including viruses and other bacteria.
- The complex microbial communities within chiggers are increasingly being investigated.
Purpose of the Study:
- To explore the diversity of the chigger microbiota.
- To investigate potential interactions within the chigger's microbial microcosm.
- To assess the role of chiggers in the transmission of various pathogens and symbionts.
Main Methods:
- Microbiota analysis of chigger populations.
- Pathogen detection and identification.
- Investigation of transmission routes.
Main Results:
- Chiggers host a surprisingly diverse microbiota, including various bacterial species and potentially viruses.
- Unidentified symbionts dominate the microbiota in certain chigger populations.
- Evidence supports vertical transmission of symbionts and potential pathogens in chiggers.
Conclusions:
- Chiggers may act as vectors for viral diseases beyond rickettsial pathogens.
- The chigger microbiota includes unidentified symbionts, highlighting knowledge gaps.
- Vertical transmission suggests intimate host-microbe relationships, not just environmental acquisition.
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