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Published on: July 20, 2022
Left atrial strain predicts improvement in left atrial functions of severe rheumatic mitral stenoses undergoing
Prabhat Sharma1, Salil Garg2, Susheel Kumar Malani3
1Department of Cardiology, Command Hospital, Udhampur, Jammu and Kashmir, India.
Insights
Peak atrial longitudinal strain (PALS) is impaired in severe mitral stenosis (MS) but improves after percutaneous transvenous mitral commissurotomy (PTMC). PALS effectively measures left atrial function and may predict PTMC success in rheumatic heart disease.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Physiology
Background:
- Rheumatic heart disease (RHD) commonly affects the mitral valve in India.
- Left atrial (LA) enlargement in RHD impacts its reservoir function.
- Peak atrial longitudinal strain (PALS) quantifies LA longitudinal function.
Purpose of the Study:
- To evaluate LA function using PALS in severe rheumatic mitral stenosis (MS) patients.
- To assess PALS changes after successful percutaneous transvenous mitral commissurotomy (PTMC).
- To determine PALS as a predictor of PTMC outcomes in MS.
Main Methods:
- Study included 50 patients with severe rheumatic MS in sinus rhythm undergoing PTMC.
- Exclusion criteria included atrial fibrillation (AF).
- PALS was measured to assess LA function before and after PTMC.
Main Results:
- PALS was significantly impaired in patients with severe symptomatic MS.
- PALS demonstrated acute enhancement following successful PTMC (P < .001).
Conclusions:
- PALS is a valuable indicator of left atrial function in MS.
- PALS may predict the success of PTMC in rheumatic mitral valve disease.
Aims:
Chronic rheumatic heart disease (RHD) is prevalent in India. The mitral valve in isolation or combination with the aortic or tricuspid valve is involved in 31.6% and 52.8% of chronic RHD patients, respectively. The left atrium (LA) functions as a reservoir during the cardiac cycle. Therefore, the LA enlargement leads to longitudinal lengthening, measured as a positive strain, permitting the measurement of the longitudinal strain of LA. This study aimed to assess the LA functions using peak atrial longitudinal strain (PALS) in patients with severe rheumatic mitral stenoses (MS) in sinus rhythm who underwent successful percutaneous transvenous mitral commissurotomy (PTMC).
Material And Methods:
We recruited 56 patients with severe rheumatic MS for the study, of which 06 PTMC procedures were considered unsuccessful. So, 50 patients of chronic severe rheumatic MS in sinus rhythm undergoing PTMC were enrolled in a tertiary care centre of the Armed Forces from August 2017 to May 2019. Patients included in the study were not consecutive, and patients with atrial fibrillation (AF) were excluded.
Results:
PALS improved post-PTMC (P < .001) in this study, effectively concluding that PALS is impaired in patients with severe symptomatic MS and is acutely enhanced after treatment.
Conclusions:
PALS is a good indicator of LA function and may predict the success of PTMC on the rheumatic mitral valve.
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