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Factors that Influence Placement of Gastrostomy Tube in Infants with Complex Congenital Heart Disease: A Single
S Sundararajan1, P Abi Habib2, H Tadbiri2
1Division of Neonatology, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, MD, USA.
Insights
Factors like longer intensive care unit stays and delayed feeding after surgery predict the need for gastrostomy tubes (G-tubes) in infants with complex congenital heart defects (CHD). These insights aid in counseling parents on postnatal outcomes.
Area of Science:
- Pediatric Cardiology
- Neonatal Surgery
- Congenital Heart Defects
Background:
- Infants with complex congenital heart defects (CHD) often require specialized feeding support.
- Predicting the need for gastrostomy tube (G-tube) placement in these infants is challenging for expectant parents.
- Identifying key factors can improve prenatal counseling and postnatal management strategies.
Purpose of the Study:
- To identify clinical factors associated with gastrostomy tube (G-tube) placement in infants diagnosed prenatally with complex congenital heart defects (CHD).
- To provide data that can enhance counseling for expectant parents regarding potential postnatal outcomes and interventions.
- To understand the relationship between feeding milestones, ventilation support, and G-tube necessity.
Main Methods:
- Retrospective review of medical records for infants with complex CHD.
- Study period: 2015-2019 at a single tertiary care center.
- Linear regression analysis used to assess risk factors for G-tube placement.
Main Results:
- 42% (44 of 105) of infants with complex CHD required G-tube placement.
- Significant predictors for G-tube placement included: increased days on non-invasive ventilation, delayed initiation of gavage-tube feeds, delayed achievement of full-volume gavage feeds, and longer intensive care unit (ICU) length of stay (LOS).
- Infants with ICU LOS exceeding the median had a 7.23-fold increased odds of requiring a G-tube.
Conclusions:
- Delayed initiation and progression of gavage-tube feeding post-cardiac surgery are significant predictors for G-tube placement.
- Increased duration of non-invasive ventilation and ICU stay are strongly associated with the need for G-tubes.
- The specific type of CHD or the necessity of cardiac surgery itself did not emerge as significant predictors for G-tube placement in this cohort.
Background:
Factors that determine the need for Gastrostomy tube (G-tube) placement in infants with complex congenital heart defects (CHD) are variable. We aim to identify factors that improve counseling of expectant parents regarding postnatal outcomes and management.
Methods:
We performed a retrospective review of medical record of infants with prenatal diagnoses of complex CHD between 2015-2019 in a single tertiary care center and assessed risk factors for G-tube placement with linear regression.
Results:
Of the 105 eligible infants with complex CHD, 44 infants required G-tube (42%). No significant association was observed between G-tube placement and chromosomal abnormalities, cardiopulmonary bypass time or type of CHD. Median days on noninvasive ventilation (4 [IQR 2-12] vs. 3 [IQR 1-8], p = 0.035), time at which gavage-tube feeds were started postoperatively (3 [IQR 2-8] vs. 2 [IQR 0-4], p = 0.0013), time to reach full-volume gavage-tube feeds (6 [IQR 3-14] vs. 5 [IQR 0-8], p = 0.038) and intensive care unit (ICU) length of stay (LOS) (41 [IQR: 21 - 90] vs. 18 [IQR: 7 - 23], p < 0.01) were associated with G-tube placement. Infants with ICU LOS duration longer than median had almost 7 times the odds of requiring a G-tube (OR: 7.23, 95% CI: 2.71-19.32; by regression).
Conclusions:
Delay in initiation and in reaching full-volume gavage-tube feeds after cardiac surgery, increased number of days spent on non-invasive ventilation and in the ICU were found to be significant predictors for G-tube placement. The type of CHD and the need for cardiac surgery were not significant predictors for G-tube placement.
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