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Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
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Related Experiment Video

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Gender differences in the young-onset persistent delusional disorder.

Rashmi Arasappa1, Nellai K Chithra2, Karishma R Kulkarni3

  • 1Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, Karnataka, India.

Asian Journal of Psychiatry
|June 4, 2023
PubMed
Summary
This summary is machine-generated.

Gender differences in young onset Persistent Delusional Disorder (PDD) show distinct patterns in delusion types, marital and employment status, and co-occurring substance dependence. Males with PDD had higher rates of substance dependence and specific delusion types compared to females.

Keywords:
Delusional disorderGender differencePersistent delusional disorderPsychosisYoung onset

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Neuroscience

Background:

  • Persistent Delusional Disorder (PDD) is a complex psychiatric condition.
  • Understanding gender-specific characteristics in young-onset PDD is crucial for targeted interventions.
  • Previous research has not fully elucidated gender differences in early-onset PDD.

Purpose of the Study:

  • To investigate and delineate gender disparities in young onset Persistent Delusional Disorder (PDD).
  • To analyze differences in psychopathology, co-morbidity, and family history between genders in early PDD.
  • To identify specific delusion subtypes more prevalent in males versus females with young onset PDD.

Main Methods:

  • Retrospective chart review of 236 subjects diagnosed with young onset PDD (onset before age 30).
  • Statistical analysis to compare gender differences in demographic, clinical, and familial variables.
  • Chi-square tests were employed to assess the significance of observed differences.

Main Results:

  • Significant gender differences were observed in marital and employment status (p<0.001).
  • Females exhibited higher rates of infidelity delusions and erotomania; males showed more body dysmorphic and persecutory delusions (p=0.009).
  • Males had significantly higher rates of substance dependence (p<0.001) and a family history of substance abuse and PDD (p<0.01).

Conclusions:

  • Gender significantly influences the presentation of psychopathology in young onset PDD.
  • Co-morbidity patterns, particularly substance dependence, differ between genders in this population.
  • Family history of substance abuse and PDD is more common in males with young onset PDD, suggesting potential genetic or environmental gender-related influences.