Effects of Perfluorocarbon Use during Rhegmatogenous Retinal Detachment Surgery on Postoperative Outcomes

Area of Science:

• Ophthalmology
• Retinal Surgery
• Vitreoretinal Diseases

Background:

• Rhegmatogenous retinal detachment (RRD) is a condition requiring surgical intervention.
• Vitrectomy is a common surgical procedure for RRD.
• Perfluorocarbon liquids (PFCLs) are sometimes used during vitrectomy.

Purpose of the Study:

• To investigate the effect of perfluorocarbon liquid (PFCL) use on retinal re-attachment rates after primary vitrectomy for RRD.
• To identify factors influencing re-detachment in RRD surgery.

Main Methods:

• Retrospective, observational, multicenter study analyzing 2,362 eyes from the Japanese vitreoretinal surgery database.
• Comparison of re-attachment rates in eyes that underwent primary vitrectomy with or without PFCL.
• Univariate and multivariate analyses to determine factors affecting re-detachment.

Main Results:

• The re-attachment rate was 91.5% in the PFCL group and 93.2% in the non-PFCL group (p=0.46).
• Multivariate analysis revealed no significant association between PFCL use and re-attachment rates (β = -0.08, p=0.46).
• Certain risk factors for re-detachment were identified in the non-PFCL group but not in the PFCL group.

Conclusions:

• Perfluorocarbon liquid (PFCL) use during initial vitrectomy for RRD does not significantly affect the rate of retinal re-attachments.
• The decision to use PFCL in RRD vitrectomy may not influence surgical outcomes regarding re-attachment.