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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

Published on: June 4, 2020

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[Utility of thromboelastography in the treatment of acquired hemophilia A]

Shuolin Wang1,2, Keiki Nagaharu1, Kazutaka Suzuki1

  • 1Department of Hematology and Oncology, Mie University Hospital.

[Rinsho Ketsueki] the Japanese Journal of Clinical Hematology
|June 4, 2023
PubMed

Acquired hemophilia A (AHA) is a bleeding disorder caused by the spontaneous development of inhibitory autoantibodies to factor VIII. Thromboelastography (TEG) is a clinical examination that assesses clot formation in the whole blood. However, its utility in the hemostatic management of AHA is unexplored. A 35-year-old man who developed AHA after abdominal surgery was treated for hemostasis with bypassing agents. The TEG R value, which was prolonged as bleeding worsened, was improved by switching to bypassing agents. We report this impressive case, which suggests that TEG can monitor hemostatic effects and is useful for the management of a bypassing agent regimen in addition to its previously acknowledged utility in clinical evaluation.

Keywords:
Acquired hemophilia AThromboelastography

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