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Related Concept Videos

Local Anesthetics: Clinical Application as Spinal Anesthesia01:11

Local Anesthetics: Clinical Application as Spinal Anesthesia

690
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
690
Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

488
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
488
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia01:30

Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia

1.1K
Depending on the target organ, local anesthetics (LAs) can be administered via various routes. In surface anesthesia, LAs are applied directly to the surface of the skin or mucous membranes. It is widely used for topical skin numbing before venipuncture or minor surgical procedures. Commonly used surface local anesthetics are lidocaine or benzocaine sprays or creams. Surface anesthesia occurs within 5 minutes and lasts for about 60 minutes. One of the main disadvantages of topical anesthesia is...
1.1K
Local Anesthetics: Chemistry and Structure-Activity Relationship01:27

Local Anesthetics: Chemistry and Structure-Activity Relationship

4.5K
Local anesthetics (LAs) are drugs that induce a temporary loss of sensation in a limited body area, preventing pain. Cocaine was the first local anesthetic discovered in the late 19th century. Cocaine is a benzoic acid ester obtained from the leaves of coca shrubs and was often used for its psychotropic effects. Cocaine was first isolated in 1860 by Albert Niemann. Sigmund Freud studied the physiological actions of cocaine. Carl Koller later introduced it into clinical practice in 1884 as a...
4.5K
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

485
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
485
Local Anesthetics: Clinical Application as Epidural Anesthesia01:29

Local Anesthetics: Clinical Application as Epidural Anesthesia

461
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
461

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Related Experiment Video

Updated: Jul 28, 2025

CO2-Lasertonsillotomy Under Local Anesthesia in Adults
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Local anesthesia for Altis

Andrea Morciano1, Giuseppe Marzo1, Dario Caliandro1

  • 1Panico Pelvic Floor Center, Department of Gynaecology and Obstetrics, Pia Fondazione 'Card. G. Panico', Tricase, Lecce, Italy.

Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy
|June 5, 2023
PubMed
Summary
This summary is machine-generated.

Local anesthesia for Altis® single incision slings is as effective as spinal anesthesia for treating stress urinary incontinence. This approach offers a safe alternative, potentially enabling outpatient procedures.

Keywords:
Altislocal anesthesiastress incontinenceurgencyurodynamics

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Laminectomy and Spinal Cord Window Implantation in the Mouse
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Area of Science:

  • Urology
  • Gynecology
  • Anesthesiology

Background:

  • Stress urinary incontinence (SUI) affects many women.
  • Single incision slings, like Altis®, are used for SUI treatment.
  • Anesthesia choice impacts patient outcomes and procedure feasibility.

Purpose of the Study:

  • To evaluate the efficacy and safety of local anesthesia for Altis® single incision sling placement.
  • To compare local anesthesia with spinal anesthesia for Altis® implantation.

Main Methods:

  • Retrospective study of 166 women with SUI undergoing Altis® implantation.
  • Patients were divided into local anesthesia (83) and spinal anesthesia (83) groups.
  • Primary endpoints: objective and subjective cure rates at 12 months. Secondary endpoint: complication evaluation.

Main Results:

  • 155 patients completed follow-up; baseline characteristics were similar.
  • Spinal anesthesia showed shorter operative time and lower intraoperative difficulty.
  • No significant differences in objective cure rates (cough stress test, urodynamics) or subjective cure rates (PGI-I, FSDS) between groups.
  • Postoperative complication rates were comparable.

Conclusions:

  • Local anesthesia is a safe and effective alternative to spinal anesthesia for Altis® sling procedures.
  • It avoids general anesthesia and supports outpatient implantation.
  • This offers a viable treatment option for women with stress urinary incontinence.