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Cognitive Impairment in Patients With Cardiac Disease: Implications for Clinical Practice
Astrid C van Nieuwkerk1,2, Ronak Delewi1,2, Frank J Wolters3,4
1Department of Cardiology, Amsterdam UMC, University of Amsterdam, the Netherlands (A.C.v.N., R.D.).
Insights
Cognitive impairment affects one in three cardiology patients, often unrecognized, impacting self-care. Early detection and management are crucial for cardiovascular disease patients with cognitive decline.
Area of Science:
- Cardiology
- Neurology
- Cognitive Science
Background:
- Cognitive impairment is prevalent in cardiovascular disease (CVD) patients, affecting up to one-third.
- Unrecognized cognitive impairment can negatively impact treatment adherence and self-management in cardiac patients.
- Shared risk factors and cardiac dysfunction contribute to cognitive decline in CVD.
Purpose of the Study:
- To review the prevalence and risk factors of cognitive impairment in common cardiac conditions.
- To discuss the impact of guideline-based treatments on cognitive function.
- To identify unmet needs and propose strategies for improved detection and management.
Main Methods:
- Literature review of studies on cognitive impairment in heart failure, coronary artery disease, and aortic valve stenosis.
- Analysis of shared risk factors between cardiovascular disease and cognitive decline.
- Evaluation of the effects of cardiac interventions and treatments on cognition.
Main Results:
- Cognitive impairment is frequently observed in patients with heart failure, coronary artery disease, and aortic valve stenosis.
- Cardiac dysfunction and shared risk factors are key contributors to cognitive impairment in this population.
- Guideline-based cardiac treatments may have variable effects on cognitive functioning.
Conclusions:
- A significant proportion of cardiovascular disease patients experience cognitive impairment, often undiagnosed.
- A systematic approach is recommended to enhance the recognition and management of cognitive impairment in cardiac care.
- Further research is needed to address knowledge gaps regarding treatment effects on cognition.
Abstract:
Cognitive impairment is common in patients with cardiovascular disease. One in 3 patients presenting at cardiology clinics have some degree of cognitive impairment, depending on the cardiac condition, comorbidities, and age. In up to half of these cases cognitive impairment may go unrecognized; however, it may affect self-management and treatment adherence. The high prevalence of cognitive impairment in patients with cardiac disease is likely due to shared risk factors, as well as direct consequences of cardiac dysfunction on the brain. Moreover, cardiac interventions may have beneficial as well as adverse effects on cognitive functioning. In this review, we describe prevalence and risk factors for cognitive impairment in patients with several common cardiac conditions: heart failure, coronary artery disease, and aortic valve stenosis. We discuss the potential effects of guideline-based treatments on cognition and identify open questions and unmet needs. Given the high prevalence of unrecognized cognitive impairment in cardiac patients, we recommend a stepwise approach to improve detection and management of cognitive impairment.
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