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Related Experiment Videos

[Mallory-Weiss syndrome].

S B Pinskiĭ, V A Ageenko, A I Bregel'

    Vestnik Khirurgii Imeni I. I. Grekova
    |March 1, 1986
    PubMed
    Summary

    Mallory-Weiss syndrome, a cause of upper gastrointestinal bleeding, is increasingly diagnosed with endoscopy. A new endoscopic hemostasis technique using Ferakryl has shown a 100% success rate, eliminating mortality in treated patients.

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    Area of Science:

    • Gastroenterology
    • Endoscopy
    • Hemorrhage Management

    Context:

    • Mallory-Weiss syndrome (MWS) is a significant cause of acute gastroduodenal hemorrhage.
    • The clinic observed MWS in 4.7% of 1392 patients with acute gastroduodenal hemorrhages over 18 years.
    • Recent advancements in urgent esophagogastroduodenoscopy have improved MWS diagnostics, increasing detection rates by 10%.

    Purpose:

    • To present the clinic's 18-year experience in diagnosing and treating Mallory-Weiss syndrome.
    • To evaluate the efficacy of endoscopic hemostasis with Ferakryl for MWS.
    • To compare outcomes of surgical, conservative, and endoscopic hemostasis methods.

    Summary:

    • Over 18 years, 65 cases of MWS were identified among 1392 patients with acute gastroduodenal hemorrhages.
    • Before endoscopic hemostasis with Ferakryl, treatment involved surgery (4/24 patients) or conservative methods (20/24 patients), with 4 deaths.
    • In the last 2.5 years, complex conservative treatment including curative endoscopy and Ferakryl achieved stable hemostasis in all 41 patients, with no fatalities.

    Impact:

    • The introduction of endoscopic hemostasis with Ferakryl has significantly improved patient outcomes for Mallory-Weiss syndrome.
    • This approach has demonstrated a 100% success rate in achieving hemostasis and has eliminated mortality in treated cases.
    • Improved diagnostic capabilities through urgent esophagogastroduodenoscopy contribute to better management of gastroduodenal hemorrhages.

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