Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

1.5K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
1.5K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

2.9K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trousseau's syndrome with cerebral infarction as the first manifestation.

American journal of translational research·2026
Same author

Characteristics of extracellular vesicle-derived lncRNAs during the progression of HBV-related hepatocellular carcinoma.

BMC cancer·2025
Same author

The burden dynamics of leukemia in China from 1990 to 2021: an epidemiological analysis of trends, risk factors, and projections to 2036.

Preventive medicine reports·2025
Same author

Paraneoplastic cerebellar degeneration combined with Lambert-Eaton myasthenia gravis syndrome in a patient positive for SOX1 antibody.

American journal of translational research·2025
Same author

Nomograms for predicting recurrence of HER2-positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics.

Cancer medicine·2024
Same author

The short-term efficacy of neoadjuvant SOX versus SOX plus immune checkpoint inhibitor following laparoscopic gastrectomy for locally advanced gastric cancer: a multicenter retrospective cohort study in China.

Cancer immunology, immunotherapy : CII·2024
Same journal

Mineralogical characterization of tobacco stalk ash.

Environmental science and pollution research international·2026
Same journal

Occurrence, distribution and risk assessment of pharmaceuticals and personal care products in Djibouti aquifer.

Environmental science and pollution research international·2026
Same journal

Anthropogenic microparticles and mercury co-occurrence in blue sharks from the Tropical Eastern Pacific.

Environmental science and pollution research international·2026
Same journal

IoT-enabled FMIND pipeline with chemical validation for microplastic contamination risk assessment in bottled water under varying storage conditions.

Environmental science and pollution research international·2026
Same journal

Retraction Note: Toward a sustainable environment: nexus between geothermal energy growth and land use change in EU economies.

Environmental science and pollution research international·2026
Same journal

Retraction Note: COVID-19: pathogenesis, advances in treatment and vaccine development and environmental impact-an updated review.

Environmental science and pollution research international·2026
See all related articles

Related Experiment Video

Updated: Jul 28, 2025

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
05:18

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

365

The effect of PM

Hao Cui1,2,3, Ye Qi1,3,4,5,6, Chunyue Guo1,3

  • 1The Third Central Clinical College of Tianjin Medical University, 83 Jintang Road, Hedong District, Tianjin, 300170, China.

Environmental Science and Pollution Research International
|June 5, 2023
PubMed
Summary
This summary is machine-generated.

Exposure to fine particulate matter (PM2.5) significantly increases mortality risk in Chinese hepatocellular carcinoma (HCC) patients. Higher PM2.5 levels correlate with greater survival impact, especially in older adults and urban residents.

Keywords:
Air pollutionCohortHepatocellular carcinomaMortalityPM2.5Particulate matter

More Related Videos

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model
07:35

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model

Published on: December 10, 2021

2.0K
Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System
08:48

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System

Published on: December 21, 2016

8.7K

Related Experiment Videos

Last Updated: Jul 28, 2025

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters
05:18

Measuring Carbon Content in Airway Macrophages Exposed to Carbon-Containing Particulate Matters

Published on: July 12, 2024

365
Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model
07:35

Aggravation of Myocardial Ischemia upon Particulate Matter Exposure in Atherosclerosis Animal Model

Published on: December 10, 2021

2.0K
Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System
08:48

Analysis of the Ambient Particulate Matter-induced Chromosomal Aberrations Using an In Vitro System

Published on: December 21, 2016

8.7K

Area of Science:

  • Environmental Health
  • Oncology
  • Epidemiology

Background:

  • Particulate matter (PM2.5) is linked to respiratory and cardiovascular issues.
  • Limited cohort evidence exists on PM2.5's impact on hepatocellular carcinoma (HCC) survival in China.
  • Understanding environmental risk factors is crucial for HCC patient outcomes.

Purpose of the Study:

  • To evaluate the association between PM2.5 exposure and mortality in HCC patients in China.
  • To quantify the risk of death associated with varying PM2.5 concentrations.

Main Methods:

  • A cohort study of 1440 HCC patients from September 2013 to December 2018.
  • PM2.5 exposure assessed using the inverse distance weighted (IDW) method.
  • Survival analysis employed Kaplan-Meier, restricted cubic splines, and Cox proportional hazards models.

Main Results:

  • HCC patients exposed to PM2.5 ≥ 58.56 μg/m3 had significantly higher mortality (79.0% vs 50.7%).
  • A linear relationship was observed between PM2.5 concentration and mortality risk.
  • Each 10-μg/m3 increase in PM2.5 elevated HCC mortality risk by 44% (HR = 1.44, P < 0.001).

Conclusions:

  • Elevated PM2.5 exposure after HCC diagnosis negatively impacts patient survival.
  • The risk of death increases with higher PM2.5 concentrations.
  • The effect of PM2.5 on HCC mortality is more pronounced in patients aged ≥60 and those in urban areas.