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Updated: Jul 27, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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Cardiomyopathy related desmocollin-2 prodomain variants affect the intracellular cadherin transport and processing

Greta Marie Pohl1, Manuel Göz2, Anna Gaertner1

  • 1Erich & Hanna Klessmann-Institute for Cardiovascular Research and Development & Clinic for Thoracic and Cardiovascular Surgery, Heart- and Diabetes Center NRW, D-32545 Bad Oeynhausen, University Hospital of the Ruhr-University Bochum, Bad Oeynhausen, Germany.

Frontiers in Cardiovascular Medicine
|June 5, 2023
PubMed
Abstract

Keywords:
DSC2arrhythmogenic cardiomyopathydesmocollin-2desmosomegenetic variantsintracellular transportprodomainsignal peptide

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