Related Experiment Video
Updated: Aug 10, 2026
06:17
Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
[Adsorbed subunit influenza vaccine: its isolation and characteristics]
Virologie
|April 1, 1986
Abstract:
Experimental batches of adsorbed subunit influenza vaccine were prepared from the envelope of glycoprotein antigens separated from the influenza virion by treatment with a cationic detergent (cetyltrimethylammonium bromide). Purified and concentrated influenza virus strains A(H1N1) and A(H3N2) were obtained by gradient centrifugation; additional purification, with a view to removing ovalbumin and structural components of the chorioallantoic membrane, was achieved by gelfiltration. The composition and biological properties of the vaccine are described.
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