Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

128
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
128
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

450
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
450
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

237
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
237
Endoscopic Procedures I: Esophagogastroduodenoscopy01:29

Endoscopic Procedures I: Esophagogastroduodenoscopy

222
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
222
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

142
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
142
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

293
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
293

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A fusion-deletion genomic-event underlies poor prognosis in young patients with luminal breast cancer.

PloS one·2026
Same author

Circulating DNA demethylation-derived cytosine analytes as emerging biomarkers.

Gene·2026
Same author

Heavy-Atom Effect Modulated Photoluminescence Properties of Trinuclear Copper(I) Clusters with Haloarylacetylene Ligands.

Molecules (Basel, Switzerland)·2026
Same author

Acupoint Sensitivity in Patients with Primary Insomnia and Its Correlation with Polysomnography and Heart Rate Variability: A Cross-Sectional Study.

Nature and science of sleep·2026
Same author

Trends and lifestyle contributions to frailty in US adults aged 50 and older: analysis of health and retirement study data (2004-2020).

BMC public health·2026
Same author

Autoimmune cerebellar ataxia with anti-Homer3 antibodies associated with herpesvirus infection: a case report and literature review.

Frontiers in immunology·2026

Related Experiment Video

Updated: Jul 27, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.1K

Endoscopic and pathological characteristics of

Shi-Yang Li1, Mei-Qi Yang1, Yi-Ming Liu1

  • 1Department of Endoscopy, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.

World Journal of Gastroenterology
|June 5, 2023
PubMed
Summary
This summary is machine-generated.

De novo colorectal cancers (CRCs) are often small and difficult to distinguish from benign polyps. These de novo CRCs show a higher metastatic potential and worse outcomes compared to carcinoma in adenoma (CIA) CRCs.

Keywords:
Carcinoma in adenomaClinical characteristicsDe novo colorectal cancerEndoscopic featuresPathological features

More Related Videos

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

18.7K
Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

12.1K

Related Experiment Videos

Last Updated: Jul 27, 2025

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.1K
Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

18.7K
Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
06:55

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging

Published on: May 11, 2014

12.1K

Area of Science:

  • Gastroenterology
  • Oncology
  • Endoscopic Imaging

Background:

  • Endoscopic advancements allow detailed investigation of intestinal tumors.
  • Distinguishing small, concealed de novo colorectal cancers (CRCs) from nonneoplastic polyps and carcinoma in adenoma (CIA) is challenging.
  • Invasive depth and metastatic potential are critical for treatment and prognosis.

Purpose of the Study:

  • To summarize endoscopic features of de novo CRCs.
  • To identify risk factors differentiating de novo CRCs from CIA.
  • To aid in diagnosis and treatment strategies for small CRCs.

Main Methods:

  • Retrospective analysis of 167 patients with endoscopically diagnosed small CRCs.
  • Exclusion of advanced CRCs and other confounding conditions.
  • Comparison of clinicopathological features and risk factors for invasion depth between de novo and CIA groups using SPSS 25.0.

Main Results:

  • Nearly half of de novo CRCs were <1 cm, predominantly in the distal colon.
  • IIc type was the most common macroscopic type for de novo CRCs.
  • Chicken skin mucosa (CSM) was a significant risk factor for deep invasion and impacted endoscopic ultrasound accuracy. High tumor budding and tumor-infiltrating lymphocytes indicated malignancy.

Conclusions:

  • This study provides a comprehensive analysis of de novo CRC endoscopic features.
  • Chicken skin mucosa (CSM) is highlighted as a key factor in invasive depth assessment.
  • De novo CRCs exhibit high metastatic potential and worse outcomes, necessitating further research.