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Updated: Jul 27, 2025

A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
Published on: January 11, 2018
Evaluation of Joint Formation in Coronoid Process Hyperplasia (Jacob's Disease) on CT and MR Imaging
Suryansh Arora1,2, Sarita Jilowa1,2, Mayank Swarnkar1,2
1Institute- Atal Bihari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Background:
Jacob's disease is a rare pathology characterized by elongation/ enlargement of coronoid process of mandible with formation of pseudoarticulation with zygomatic arch. It presents clinically as restricted mouth opening and is often misdiagnosed as temporomandibular joint pathology.
Case Presentation:
We performed cross sectional imaging and evaluation of Jacob's disease in a 14-year-old girl with restricted mouth opening, CT images including Multiplanar Reconstruction and Volume Rendered Technique revealed enlarged left coronoid process of mandible while open mouth CT images and MR images concluded the presence of joint between enlarged coronoid process and zygomatic arch.
Conclusions:
Coronoid process hypertrophy and Jacob's disease are important differentials which should be considered in evaluation of restricted mouth opening. We propose that apart from CT, MR imaging should be considered in such cases for better pre-operative evaluation of joint formation.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s12070-022-03323-7.
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