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Updated: Jul 27, 2025
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Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
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Submandibular Gland in Neck Dissection: Necessary Fatality or Unfortunate Prey?
Tashnin Rahman1, Kirti Khandelwal1, Srinivas Bannoth1
1Dr. B. Borooah Cancer Institute, Guwahati, India.
Summary
Submandibular gland involvement in oral cancer is rare (3.8%), but associated with advanced disease factors. Preservation may be possible in early buccal mucosa cancers without specific risk factors.
Area of Science:
- Oncology
- Head and Neck Surgery
- Oral Pathology
Background:
- Submandibular gland excision is standard in neck dissections.
- Understanding submandibular gland involvement in oral cancer is crucial for surgical decision-making.
Purpose of the Study:
- To determine the prevalence of submandibular gland involvement in squamous cell oral carcinomas.
- To identify factors associated with submandibular gland metastasis in oral cancer patients.
Main Methods:
- Retrospective observational study of 317 patients.
- Data collected from January 2018 to February 2020.
- Analysis of submandibular gland involvement and associated clinicopathological factors.
Main Results:
- The prevalence of submandibular gland involvement was 3.8%.
- Increased risk associated with level-Ib node involvement (OR 13.6), extranodal extension (OR 67), and perineurial invasion (OR 5).
- These factors were statistically significant (p < 0.001 for nodes and ENE, p = 0.003 for PNI).
Conclusions:
- Submandibular gland preservation may be feasible in early-stage buccal mucosa cancers.
- Preservation is advisable when extranodal extension and level-Ib involvement are absent.
- This approach can help avoid unnecessary morbidity associated with gland excision.
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