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Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
04:12

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid

Published on: January 19, 2024

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Oral Tranexamic Acid for the Treatment of Melasma: Evidence and Experience-Based Consensus Statement from Indian

Kiran Godse1, Rashmi Sarkar2, Venkataram Mysore3

  • 1From the Department of Dermatology, Dr. DY Patil Medical College, Navi Mumbai, Maharashtra, India.

Indian Journal of Dermatology
|June 5, 2023
PubMed

Insights

Oral tranexamic acid (TXA) offers a promising treatment for melasma, a difficult skin condition. This expert consensus provides guidance on using oral TXA effectively for melasma patients seeking better outcomes.

Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Melasma is a persistent facial hyperpigmentation disorder with limited treatment satisfaction.
  • Tranexamic acid (TXA), an anti-fibrinolytic agent, shows potential for melasma treatment.

Purpose of the Study:

  • To establish an expert consensus on the use of oral tranexamic acid (TXA) for melasma treatment.
  • To provide clinical guidance based on existing literature and expert experience.

Main Methods:

  • A review of current literature on tranexamic acid (TXA) for melasma.
  • Consensus development among Indian experts regarding oral TXA application.

Main Results:

  • Tranexamic acid (TXA) demonstrates efficacy and tolerability in melasma patients.
  • Oral TXA can be used as monotherapy or adjunctively with other treatments.

Conclusions:

  • There is a need for standardized guidelines for oral tranexamic acid (TXA) in melasma management.
  • This consensus aims to aid clinicians in the appropriate use of oral TXA for melasma.
Keywords:
Adverse eventanti-fibrinolytic agentevidencetreatment outcome

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