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Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Immediate sequential vs delayed sequential bilateral cataract surgery: systematic review and meta-analysis.

Francesco Aiello1, Gabriele Gallo Afflitto, Katherine Leviste

  • 1From the Ophthalmology Unit, Department of Experimental Medicine, University of Rome "Tor Vergata," Rome, Italy (Aiello, Gallo Afflitto, Nucci); Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida (Gallo Afflitto, Leviste, Swaminathan, Yoo); Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom (Maurino); Vienna Institute for Research in Ocular Surgery (VIROS), Hanusch Hospital, Vienna, Austria (Findl).

Journal of Cataract and Refractive Surgery
|June 5, 2023
PubMed
Summary
This summary is machine-generated.

Immediate sequential bilateral cataract surgery (ISBCS) shows comparable safety and efficacy to delayed surgery (DSBCS). However, ISBCS may have a slightly higher risk of posterior capsule rupture, warranting further investigation.

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Evidence-Based Medicine

Background:

  • Cataract surgery is a common procedure globally.
  • Sequential bilateral cataract surgery (ISBCS and DSBCS) are surgical approaches.
  • Evaluating the safety and efficacy of ISBCS versus DSBCS is crucial for clinical decision-making.

Approach:

  • Systematic review and meta-analysis of 13 studies.
  • Inclusion of data from 11,068,622 participants (18,802,043 eyes).
  • Comprehensive analysis of postoperative visual acuity, refractive outcomes, and complications like endophthalmitis and posterior capsule rupture (PCR).

Key Points:

  • No statistically significant differences in visual acuity, refractive outcomes, endophthalmitis, corneal edema, or pseudophakic macular edema between ISBCS and DSBCS.
  • A higher risk of posterior capsule rupture (PCR) was observed in the ISBCS group based on nonrandomized studies (RR, 1.34; P = .0081).
  • ISBCS demonstrates an acceptable safety-efficacy profile, similar to DSBCS.

Conclusions:

  • Immediate sequential bilateral cataract surgery (ISBCS) is a viable option with a safety profile comparable to delayed surgery (DSBCS).
  • Further research is recommended to explore risk factors for surgical complications, patient-reported outcomes, and cost-effectiveness.
  • The findings support the continued use of ISBCS while acknowledging the need for vigilance regarding PCR risk.