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Lens thickness in atopic cataract: case-control study.

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  • 1From the Department of Ophthalmology, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan (Iida, Masuda, Sano, Ichihara, Komatsu, Nakano); Roppongi Shiba Eye Clinic, Minato-ku, Tokyo, Japan (Shiba); Iwaki Eye Clinic, Sumida-ku, Tokyo, Japan (Iwaki); Oki Eye Surgery Center, Toshima-ku, Tokyo, Japan (Oki); Department of Preventative Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan (Tatemichi).

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|June 5, 2023
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Summary

Eyes with atopic cataracts have thinner lenses compared to normal or nonatopic cataracts. This lens thinning is linked to anterior subcapsular opacity, a common feature of atopic cataracts.

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Area of Science:

  • Ophthalmology
  • Ocular Biometry

Background:

  • Atopic cataracts are a specific type of lens opacity associated with atopic diseases.
  • Understanding the biometry of atopic cataracts is crucial for diagnosis and management.

Purpose of the Study:

  • To investigate the association between atopic cataracts and lens thickness.
  • To compare lens thickness in patients with atopic cataracts, nonatopic cataracts, and normal lenses.

Main Methods:

  • A retrospective matched case-control study was conducted.
  • Analyzed 31 eyes with atopic cataracts, 62 with nonatopic cataracts, and 31 normal lenses, matched for age and sex.
  • Lens thickness (LT) was measured and analyzed using statistical methods including repeated-measures analysis of variance and multivariate logistic regression.

Main Results:

  • Eyes with atopic cataracts exhibited significantly thinner lenses (mean LT 3.76 mm) compared to nonatopic cataracts (3.94 mm) and normal lenses (4.11 mm).
  • A thinner LT was correlated with anterior subcapsular cataract (ASC) (OR, 5.61) and negatively with age.
  • ASC was more prevalent in atopic cataracts (77.4%) than in nonatopic cataracts (38.7%).

Conclusions:

  • Lenses in eyes with atopic cataracts are thinner than in control groups.
  • Atopic cataracts often present with anterior subcapsular opacity, which is associated with this observed lens thinning.