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Updated: Jul 27, 2025

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
Published on: August 7, 2017
Conditional cross-map-based technique: From pairwise dynamical causality to causal network reconstruction
Liufei Yang1,2, Wei Lin1,3,4, Siyang Leng1,5
1Research Institute of Intelligent Complex Systems, Fudan University, Shanghai 200433, China.
Abstract:
Causality detection methods based on mutual cross mapping have been fruitfully developed and applied to data originating from nonlinear dynamical systems, where the causes and effects are non-separable. However, these pairwise methods still have shortcomings in discriminating typical network structures, including common drivers, indirect dependencies, and facing the curse of dimensionality, when they are stepping to causal network reconstruction. A few endeavors have been devoted to conquer these shortcomings. Here, we propose a novel method that could be regarded as one of these endeavors. Our method, named conditional cross-map-based technique, can eliminate third-party information and successfully detect direct dynamical causality, where the detection results can exactly be categorized into four standard normal forms by the designed criterion. To demonstrate the practical usefulness of our model-free, data-driven method, data generated from different representative models covering all kinds of network motifs and measured from real-world systems are investigated. Because correct identification of the direct causal links is essential to successful modeling, predicting, and controlling the underlying complex systems, our method does shed light on uncovering the inner working mechanisms of real-world systems only using the data experimentally obtained in a variety of disciplines.
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Cross Product
The magnitude of the cross product is obtained by multiplying the magnitude of both the vectors and the sine of the angle between them. This means that a larger angle between the vectors will lead to a greater magnitude of the cross product.