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Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
Thrombosis, Septic Emboli, and Multiple Abscesses Triggered by
Olaniyi Fadeyi1, Zetha Sovyanhadi1, Lakshita Gupta1
1West Anaheim Medical Center, Anaheim, CA, USA.
Abstract:
Urinary tract infection and pneumonia are common diseases caused by Klebsiella pneumoniae. In rare circumstances, Klebsiella pneumoniae has been associated with abscess formation, thrombosis, septic emboli, and infective endocarditis. We report a 58-year-old woman with a past medical history of uncontrolled diabetes who presented with abdominal pain along with swelling in the left third finger and left calf. Further work-up revealed bilateral renal vein thrombosis, inferior vena cava thrombosis, septic emboli, and perirenal abscess. All cultures were positive for Klebsiella pneumoniae. This patient was aggressively managed with abscess drainage, intravenous antibiotics, and anticoagulation. Diverse thrombotic pathologies associated with Klebsiella pneumoniae pathogen as documented in literature were also discussed.
Insights
Klebsiella pneumoniae can cause severe infections, including rare cases of thrombosis and abscesses. This case highlights a patient with uncontrolled diabetes who developed extensive thrombosis and a perirenal abscess due to Klebsiella pneumoniae.
Area of Science:
- Infectious Diseases
- Vascular Medicine
- Nephrology
Background:
- Klebsiella pneumoniae is a common pathogen causing urinary tract infections and pneumonia.
- Rarely, K. pneumoniae infections can lead to severe complications such as abscesses, thrombosis, septic emboli, and infective endocarditis.
- Uncontrolled diabetes is a known risk factor for severe infections.
Conclusions:
- Klebsiella pneumoniae can cause severe and life-threatening thrombotic complications and abscess formation, particularly in immunocompromised individuals like those with uncontrolled diabetes.
- Aggressive management including antibiotics, abscess drainage, and anticoagulation is crucial for favorable outcomes.
- This case underscores the importance of considering K. pneumoniae in the differential diagnosis of severe infections with thrombotic events.
Related Concept Videos
Venous Thrombosis I: Introduction
Pulmonary Embolism I: Introduction
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Endocarditis II: Clinical Features of Infective Endocarditis
Urinary Tract Infection II: Pathophysiology
Venous Thrombosis III: Interprofessional Care

