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Real-World User and Clinician Perspective and Experience with MiniMed™ 780G Advanced Hybrid Closed Loop System
Jothydev Kesavadev1, Anjana Basanth2, Gopika Krishnan2
1Jothydev's Diabetes Research Center, JDC Junction, Mudavanmugal, Trivandrum, Kerala, 695032, India. jothydev@gmail.com.
Summary
The advanced hybrid closed loop (AHCL) MiniMed™ 780G system provides excellent glycemic control for type 1 diabetes (T1DM) management, significantly reducing hypoglycemia. User satisfaction is high, though education on carb counting and system use is crucial for optimal performance.
Area of Science:
- Endocrinology and Metabolism
- Biomedical Engineering
- Diabetes Technology
Background:
- The MiniMed™ 780G is an advanced hybrid closed loop (AHCL) system designed to automate insulin delivery based on continuous glucose monitoring (CGM) data.
- This system adjusts basal insulin every 5 minutes and provides automatic correction boluses to manage sensor glucose values in individuals with type 1 diabetes (T1DM).
Purpose of the Study:
- To evaluate the real-world performance of the AHCL MiniMed™ 780G system in individuals with T1DM.
- To assess user and healthcare provider perspectives and satisfaction with the AHCL system.
- To analyze glycemic outcomes and identify key themes related to system usage.
Main Methods:
- Conducted peer group discussions with adults with T1DM, parents of children with T1DM, and healthcare providers (HCPs).
- Analyzed qualitative data from discussions, categorizing themes by two independent researchers.
- Examined quantitative glycemic data from the AHCL system uploaded to CareLink software, including Time in Range (TIR), Time Below Range (TBR), Time Above Range (TAR), and Glucose Management Indicator (GMI).
Main Results:
- Users reported high satisfaction with the AHCL system, experiencing consistent glucose values and minimal hypoglycemia.
- Achieved excellent glycemic control: mean GMI of 6.4%, TIR of 83.0%, and 0% TBR* (<54 mg/dL). All users exceeded 70% TIR.
- Identified key themes including managing expectations, carbohydrate counting accuracy, technical challenges (sensor connectivity, cannula issues), and the importance of user training.
Conclusions:
- The AHCL MiniMed™ 780G system demonstrates robust glycemic control and effectively minimizes hypoglycemia in T1DM management.
- User satisfaction is high, indicating a positive real-world performance.
- Comprehensive training for both users and HCPs is essential for maximizing the system's benefits and addressing potential limitations.
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