Related Experiment Video
Updated: Jul 27, 2025

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
Published on: May 12, 2019
Amphibian metamorphosis: An exquisite model for hormonal regulation of postembryonic development in vertebrates
1Division of Developmental Biochemistry, National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK.
Abstract:
Metamorphosis in invertebrates and vertebrates is an ideal model for studying mechanisms of postembryonic development regulated by external signals. Amphibian metamorphosis shares many similarities with mammalian development in the perinatal period. The precocious induction in vivo and in culture of amphibian metamorphosis by exogenous thyroid hormones and its retardation or inhibition by prolactin, have allowed the analysis of such characteristic features of postembryonic development as morphogenesis, tissue remodelling, gene reprogramming and programmed cell death. Recent studies on metamorphosis have revealed the important role played by such processes as auto- and cross-regulation of hormone receptor genes and by cell death or apoptosis, as in the maturation of the central nervous system, tissue restructuring and organolysis.
More Related Videos
11:13Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
Published on: February 2, 2016
09:22Manipulation and In Vitro Maturation of Xenopus laevis Oocytes, Followed by Intracytoplasmic Sperm Injection, to Study Embryonic Development
Published on: February 9, 2015
Related Concept Videos
Gastrulation
Development of the Sexual Organs in the Embryo and Fetus
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
Lampbrush Chromosomes
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops...
Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...