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EARLY HISTOGENESIS OF TRANSPLANTED MOUSE MAMMARY GLANDS III. PARENCHYMAL-STROMAL INTERACTIONS

Kazumasa Hoshino1, Frank Martin1, Mitsuo Machino1

  • 1Cell Biology Research Laboratory, Department of Anatomy, Faculties of Medicine and Dentistry, University of Manitoba, Winnipeg, Manitoba R3E OW3, Canada.

Development, Growth & Differentiation
|June 7, 2023
PubMed

Mammary isografts dissociated in gland-free fat pads in 24 hr but regenerated single glands. Isografts in the anterior chamber of the eye did not dissociate but regenerated only after collagenase treatment and retransplantation to gland-free fat pads.

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The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
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