Digoxin intoxication in children and young adults

Acute digoxin intoxication in children and young adults generally occurs in three distinct age groups: in infants, a pharmacokinetically disadvantaged age group, who are given an excessive dose parenterally and invariably die from the overdose; in toddlers, a pharmacokinetically favored age group, who ingest the drug accidentally and usually recover from the overdose, and in older children and young adults, who occupy an intermediate position with respect to pharmacokinetics and prognosis.