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Related Experiment Video

Updated: Jul 27, 2025

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Published on: February 17, 2017

Trehalose and its Diverse Biological Potential.

Eva Sharma¹, P S Shruti¹, Shagun Singh¹

¹Department of Human Genetics and Molecular Medicine, Molecular Medicine Laboratory, Central University of Punjab, Ghudda, Bathinda, India.

Current Protein & Peptide Science

|June 7, 2023

Summary

Trehalose, a natural disaccharide, shows significant therapeutic potential due to its stability and preservative qualities. This review explores its anticancer properties and role in modulating various disease pathways.

Keywords:

Parkinson's and Huntington's diseases PrPSc aggregates Trehalose's antiinflammatory biological potential polymorphs

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Area of Science:

Biochemistry
Pharmacology
Cell Biology

Background:

Trehalose (mycose) is a naturally occurring disaccharide with broad industrial and biological applications.
Its inertness and stability at variable temperatures facilitate its use in preservation and therapeutics.

Approach:

This review synthesizes existing research on trehalose's therapeutic applications.
Focuses on its role as a cryoprotectant, protein stabilizer, and potential treatment for various diseases.

Key Points:

Trehalose demonstrates anticancer properties by modulating cancer cell metabolism and molecular pathways.
It plays a role in neuroprotection, stem cell preservation, and protein stabilization.
Its therapeutic potential extends to managing diseases through autophagy modulation, anti-aging effects, and anti-metastasis activities.

Conclusions:

Trehalose exhibits diverse biological potential, particularly in therapeutic applications.
Further research into trehalose as a therapeutic agent is warranted for various diseases.
Its multifaceted roles highlight its significance in drug development and disease management.