Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sudesh Gourav1, Immaculata Xess1, Ashit Bhushan Xess1

  • 1Department of Microbiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Medical Mycology Case Reports
|June 7, 2023
PubMed
Summary

Lodderomyces elongisporus is a rare cause of invasive fungal infections, often missed by standard yeast identification methods. Advanced techniques like MALDI-TOF MS and DNA sequencing are crucial for accurate diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a Sensitive and Specific Novel qPCR Assay for Simultaneous Detection and Differentiation of Mucormycosis and Aspergillosis by Melting Curve Analysis.

Frontiers in fungal biology·2023
Same author

Debris flow simulation and modeling of the 2021 flash flood hazard caused by a rock-ice avalanche in the Rishiganga River valley of Uttarakhand.

Environmental monitoring and assessment·2023
Same author

Utility of in-house and commercial PCR assay in diagnosis of Covid-19 associated mucormycoss in an emergency setting in a tertiary care center.

Journal of medical microbiology·2023
Same author

Novel biogenic silver nanoconjugates of Abrus precatorius seed extracts and their antiproliferative and antiangiogenic efficacies.

Scientific reports·2023
Same author

The Role of Adjunctive Chemical Solutions in the Treatment of Odontogenic Keratocysts: A Scoping Review.

Cureus·2023
Same author

Identification of potential inhibitors of HER2 targeting breast cancer-a structure-based drug design approach.

Journal of biomolecular structure & dynamics·2023

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Clinical Microbiology

Background:

  • Invasive fungal infections pose significant challenges in clinical settings.
  • Accurate identification of fungal pathogens is critical for effective treatment.
  • Lodderomyces elongisporus is an emerging cause of opportunistic fungal infections.

Observation:

  • Routine phenotypic identification methods frequently misidentify or fail to identify Lodderomyces elongisporus.
  • This yeast can cause severe invasive infections, including fungemia.
  • A pediatric case presented with fungemia, infective endocarditis, and intracerebral bleeding.

Findings:

  • Chromogenic media, MALDI-TOF MS, and DNA sequencing are effective for accurate identification of Lodderomyces elongisporus.
Keywords:
DNA sequencingFungemiaLodderomyces elongisporusMALDI-TOF MSVentricular septal defect

Related Experiment Videos

  • The study highlights the diagnostic limitations of traditional yeast identification techniques.
  • Successful identification relies on utilizing advanced microbiological methods.

    • Implications:

    • Improved diagnostic strategies are needed to detect rare yeasts like Lodderomyces elongisporus.
    • Early and accurate diagnosis can lead to timely and appropriate antifungal therapy.
    • This case underscores the importance of considering rare fungal pathogens in immunocompromised or post-surgical patients.