Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

3.4K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biomechanical comparison of two-screw and four-screw zero-profile fusion devices in anterior cervical discectomy and fusion using finite element analysis.

Scientific reports·2026
Same author

A bioactive microflower doped triple-network hydrogel for immunomodulation-mediated angio/osteogenesis coordination in mandibular bone regeneration.

Materials horizons·2026
Same author

The effect of low muscle mass on neck disorder and cervical movement kinematics in university students: A comparative study.

Clinical biomechanics (Bristol, Avon)·2026
Same author

From Design to Application: Advanced Cellulose Scaffolds for Engineered Tissue Regeneration.

Polymers·2026
Same author

Mild Photothermal Stimulation Driven Nanoparticles Hybrid Dual-Network Hydrogels for Bone Repair.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Wireless magnetoelectric hydrogel spray reprograms the CXCL12-autophagy axis for spatiotemporally controlled cervical nerve root regeneration.

Biomaterials·2026

Related Experiment Video

Updated: Jul 27, 2025

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
06:05

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Published on: July 14, 2023

1.1K

Self-healing hydrogels for bone defect repair.

Weiwei Li1, Yanting Wu1, Xu Zhang1

  • 1State Key Laboratory of Oral Diseases, National Clinical Research Centre for Oral Diseases, West China Hospital of Stomatology, Sichuan University Chengdu 610041 China liaojinfeng.762@163.com.

RSC Advances
|June 7, 2023
PubMed
Summary
This summary is machine-generated.

Self-healing hydrogels offer a promising solution for bone defect repair, overcoming limitations of traditional bone grafting. This review explores their potential in bone tissue engineering (BTE) for enhanced bone regeneration.

More Related Videos

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.2K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

Related Experiment Videos

Last Updated: Jul 27, 2025

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration
06:05

Author Spotlight: Enhancing Bone Regeneration with Vascularized Artificial Cartilage Integration

Published on: July 14, 2023

1.1K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.2K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Orthopedic Surgery

Background:

  • Severe bone defects from trauma, infection, or tumor resection exceed the body's natural regeneration capacity.
  • Current bone grafting methods, while standard, present significant drawbacks like inflammation and secondary trauma.
  • Bone tissue engineering (BTE) presents an alternative, utilizing scaffolds like hydrogels for bone repair.

Purpose of the Study:

  • To review the application of self-healing hydrogels in bone defect repair.
  • To discuss recent advancements in self-healing hydrogel technology for BTE.
  • To identify challenges hindering clinical translation and market adoption.

Main Methods:

  • Literature review focusing on self-healing hydrogels for bone defect repair.
  • Analysis of hydrogel properties relevant to bone tissue engineering (e.g., hydrophilicity, porosity, biocompatibility).
  • Examination of self-healing mechanisms and their impact on hydrogel performance.

Main Results:

  • Self-healing hydrogels demonstrate potential as advanced scaffolds for BTE due to their unique properties.
  • These materials can autonomously repair damage, maintaining critical characteristics for bone regeneration.
  • Significant research progress has been made in developing and applying these hydrogels.

Conclusions:

  • Self-healing hydrogels represent a promising strategy for addressing critical-size bone defects.
  • Further research and development are necessary to overcome existing challenges for clinical application.
  • Increased market penetration requires addressing hurdles in clinical translation and manufacturing.